American Board of Surgery Qualifying Exam (ABS QE) Practice Test

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Prepare for the American Board of Surgery Qualifying Exam with detailed quizzes. Study with flashcards and multiple-choice questions to master the ABS QE topics. Get all the hints and explanations you need to succeed on your first attempt!

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Which tumor type is a common manifestation of neurofibromatosis?

Osteosarcoma
Peripheral nerve sheath tumors
Gastrointestinal stromal tumors
Chondrosarcoma

The correct answer is: Peripheral nerve sheath tumors

Neurofibromatosis is a genetic disorder characterized by the presence of multiple benign tumors called neurofibromas that arise from peripheral nerves. These tumors can develop along any peripheral nerve in the body and are a classic manifestation of the condition. In neurofibromatosis type 1 (NF1), which is the most common form of the disorder, individuals frequently develop multiple benign neurofibromas over their lifetime, often starting in childhood. These tumors can appear anywhere on the body and may cause symptoms depending on their size and location, but they are typically non-cancerous. Peripheral nerve sheath tumors, which encompass neurofibromas and schwannomas, are directly related to neurofibromatosis, making this tumor type a definitive manifestation of the disease. Other tumors mentioned in the question, like osteosarcoma, gastrointestinal stromal tumors, and chondrosarcoma, are not typical features of neurofibromatosis. While patients with neurofibromatosis can have other types of tumors, the direct association and prevalence of peripheral nerve sheath tumors link them specifically as common manifestations of neurofibromatosis.