American Board of Surgery Qualifying Exam (ABS QE) Practice Test

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What structure is derived from the 4th pharyngeal pouch?

  1. Superior parathyroid gland

  2. Inferior parathyroid gland

  3. Thymus

  4. Pituitary gland

The correct answer is: Superior parathyroid gland

The structure derived from the 4th pharyngeal pouch is the superior parathyroid gland. During embryonic development, the pharyngeal pouches give rise to various organs and structures in the neck region. Specifically, the 4th pharyngeal pouch is responsible for the formation of the superior parathyroid glands, which play a critical role in regulating calcium levels in the body through the production of parathyroid hormone. The thymus, which is important for immune function, actually develops from the 3rd pharyngeal pouch along with the inferior parathyroid glands. The inferior parathyroid glands, in turn, also arise from the 3rd pharyngeal pouch, leading to their lower position relative to the superior parathyroids. The pituitary gland, meanwhile, is not derived from the pharyngeal pouches but is instead formed from the ectoderm in the region of the developing brain. Understanding the origins of these structures is crucial in the study of embryology and their implications in surgical practice, as knowing the anatomical relationships can assist in surgical planning and management of conditions involving these glands.