American Board of Surgery Qualifying Exam (ABS QE) Practice Test

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Prepare for the American Board of Surgery Qualifying Exam with detailed quizzes. Study with flashcards and multiple-choice questions to master the ABS QE topics. Get all the hints and explanations you need to succeed on your first attempt!

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What is the primary role of Type 3 collagen?

Provides strength to skin and a framework for healing wounds
Supports structure in bones
Aids in the formation of basement membranes
Forms the core of cartilaginous structures

The correct answer is: Provides strength to skin and a framework for healing wounds

The primary role of Type 3 collagen is to provide strength to skin and serve as a framework for healing wounds. Type 3 collagen is a fibrillar collagen, which means it forms loose, reticular fibers that are particularly abundant in soft tissues such as the skin, blood vessels, and internal organs. This collagen type is especially important during the wound healing process, where it is often deposited in the early stages to support new tissue formation and repair. As healing progresses, Type 3 collagen is eventually replaced by Type 1 collagen, which provides greater tensile strength and structure. The presence of Type 3 collagen is essential in granulation tissue, where it facilitates the rebuilding of the extracellular matrix and contributes to the stability and strength of the newly formed tissue. This makes it critical for effective wound healing and tissue regeneration.